By Michael Parmely
You'll by no means locate a neater, extra effective, and extra concentrated solution to ace immunology and immunology-related questions about the USMLE and path examinations than the USMLE highway Map. Designed to supply greatest studying in minimal time, this thoroughly updated USMLE street Map deals a concise, inventive, and well-illustrated method of learning immunology.
The correct approach - the appropriate questions - definitely the right results
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Extra resources for USMLE Road Map: Immunology
Transcription ends at a stop codon that follows the rearranged Cκ segment. 3. Intervening RNA and nonjoined Jκ segments are removed by processing the primary RNA transcript. 4. A messenger RNA (mRNA) is produced by splicing and is then polyadenylated and translated into a κ chain polypeptide. E. The same process permits the expression of a rearranged λ locus. CHROMOSOMAL TRANSLOCATIONS TO IG LOCI • Many malignant lymphoid cells, including Burkitt s lymphoma and multiple myeloma, show chromosomal translocations that involve the Ig loci.
Lymphocytes recognize their antigens with cell surface antigen receptors. 3. The receptor on a given lymphocyte is specific for only one antigen. 4. Antigen binding to the receptor induces the expansion of a clone of cells, all with identical receptor specificity. 5. The antigen receptor on a given lymphocyte is uniform and identical to the antibody molecules secreted by the cell. B. The theory has proven correct for both B and T lymphocytes with the following exceptions: 1. The B cell antigen receptor is actually a modified form of an antibody molecule (Chapter 4).
C. T cell determinants are not limited to surface exposed regions of proteins and can be derived from internal hydrophobic protein domains. II. Antibodies A. All antibodies are immunoglobulins (Igs). B. Igs are a homologous family of proteins with considerable structural heterogeneity. C. Most Igs migrate in the “gamma” region upon serum protein electrophoresis and are therefore called γ-globulins (Figure 3–1). INTRAVENOUS IMMUNOGLOBULIN (IVIG) • Immunoglobulins (γ-globulins) are routinely given to patients for the prevention or treatment of various diseases.