By Kenneth P. Murphy
Univ. of Iowa, Iowa urban. deals protein and biophysical chemists a source for gaining how to comprehend and symbolize the root for the steadiness of the biologically lively local states of proteins. information significant cutting edge recommendations in use and emphasizes the idea at the back of each one experimental strategy.
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Extra info for Protein Structure, Stability, and Folding (Methods in Molecular Biology)
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This estimation must be done in a way that avoids the subtraction of large numbers inherent to separate calculations of internal interactions and hydration. In our calculations, we decided to make the coefficients in Eq. 4 a function of the interior packing in the protein. Thus far, the best agreement with the experimental results have been obtained when the the coefficients are scaled in terms of the average number of nonbonded atoms that are within 3 Å of solvent-buried atoms within the protein.