Download Natural Products: Drug Discovery and Therapeutic Medicine by Lixin Zhang, Arnold L. Demain PDF

By Lixin Zhang, Arnold L. Demain

A clean exam of the earlier successes of ordinary items as medicinal drugs and their new destiny from either traditional and new applied sciences. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now give the chance to quickly overview the actions of extracts in addition to purified elements derived from microbes, crops, and marine organisms. The authors follow those how to new ordinary product drug discoveries, to microbial range, to precise teams of goods (Chinese natural medicines, antitumor medicinal drugs from microbes and crops, terpenoids, and arsenic compounds), and to precise resources (the sea, rainforest, and endophytes). those new possibilities express how examine and improvement developments within the pharmaceutical can boost to incorporate either man made compounds and normal items, and the way this paradigm shift should be extra efficient and efficacious.

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