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By Walid E. Khalbuss

Cytopathology tender Tissue and Bone Lesions via Walid E. Khalbuss and Anil V. Parwani will satisfy the necessity for an easy-to-use and authoritative synopsis of sentimental tissue and bone cytopathology. This quantity, a part of the necessities in Cytopathology publication sequence, matches into the lab coat pocket and is perfect for portability and fast reference. every one quantity within the sequence is seriously illustrated with an entire colour artwork software, whereas the textual content follows a ordinary define structure. Walid E. Khalbuss, MD, PhD, FIAC is affiliate Professor of Pathology on the collage of Pittsburgh scientific middle - Shadyside health center, Pittsburgh, Pennsylvania. Anil V. Parwani, MD, PhD, is affiliate Professor of Pathology on the collage of Pittsburgh clinical middle - Shadyside health center, Pittsburgh, Pennsylvania.

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2. Kilpatrick SE, Ward WG, Cappellari JO, Bos GD. Fine-needle aspiration biopsy of soft tissue sarcomas. A cytomorphologic analysis with emphasis on histologic subtyping, grading, and therapeutic significance. Ann Diagn Pathol. 1999;3(1):48–61. 3. Handa U, Bhutani A, Mohan H, Bawa AS. Role of fine needle aspiration cytology in nonneoplastic testicular and scrotal lesions and male infertility. Acta Cytol. 2006;50(5):51–57. 4. Hummel P, Cangiarella JF, Cohen JM, Yang G, Waisman J, Chhieng DC. Transthoracic fine-needle aspiration biopsy of pulmonary spindle­ cell and mesenchymal lesions: a study of 61 cases.

Pap stain, both left ´ 400, right ´ 200) ● ● Common sites are subcutaneous tissue of the buttock or ­abdomen of obese persons. Resemble adipose tissue tumors and may be deep-seated. Cytomorphology of Fat Necrosis ● ● ● Variable numbers of foam cells, giant cells, and elongated epithelioid cells with dark nuclei and lipid-laden and hemosiderinladen macrophages. The large, foreign-body giant cells may show intracytoplasmic inclusions. Leukocytes, cholesterol crystals, and calcification may also be seen.

Inflammatory cells are scanty. Ancillary Studies Prussian blue+; Vimentin+, CD68+, Calponin+; Cytokeratin−, S100−, and CD34−, Ki67 (low index). Differential Diagnosis ● ● Soft tissue giant cell tumor of low malignant potential (less heterogeneous population of cells, no prominent stromal hyalinization), melanoma, Sarcomas. 3) ● ● ● ● ● ● ● ● Also known as osteoclastoma 4% of all primary bone tumors. Ages 20–40 years; more common in Asian countries Knee is common site (distal femur, proximal tibia), distal radius, and sacrum.

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