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Extra info for British National Formulary 61

Sample text

Congenital abnormalities When an infant is born with a congenital abnormality or there is a malformed aborted fetus doctors are asked to consider whether this might be an adverse reaction to a drug and to report all drugs (including self-medication) taken during pregnancy. Erythema multiforme or Stevens-Johnson syndrome may follow the use of a wide range of drugs including antibacterials, antiretrovirals, sulfonamide derivatives, and anticonvulsants; the oral mucosa may be extensively ulcerated, with characteristic target lesions on the skin.

Uk (in cases of emergency, telephone (020) 7035 0484). Applications must be supported by a covering letter from the prescriber and should give details of: . the patient’s name and address; . the quantities of drugs to be carried; . the strength and form in which the drugs will be dispensed; . the country or countries of destination; . the dates of travel to and from the United Kingdom. Applications for licences should be sent to the Home Office, Drugs Licensing, Peel Building, 2 Marsham Street, London, SW1P 4DF.

Serious reactions include those that are fatal, life-threatening, disabling, incapacitating, or which result in or prolong hospitalisation; they should be reported even if the effect is well recognised. Examples include anaphylaxis, blood disorders, endocrine disturbances, effects on fertility, haemorrhage from any site, renal impairment, jaundice, ophthalmic disorders, severe CNS effects, severe skin reactions, reactions in pregnant women, and any drug interactions. Reports of serious adverse reactions are required to enable comparison with other drugs of a similar class.

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