By Professor Klaus Kayser M.D., Ph.D. (auth.)
All ailments regarding the lung are awarded in alphabetical order. each one is mentioned within the similar approach less than the subheadings of definition, epidemiology, pathophysio- logy, medical analysis, radiology, gross and micro patho- logy, histomorphological descriptors, exact stains, corridor- mark of analysis and differential diagnosis.
"An encyclopedic selection of phrases facing illnesses and/or pathological stipulations of the breathing organs with the purpose to offer the reader quick information regarding the fundamental elements. This encyclopedic resource will be steered not just to pathologists but additionally to clinicians and practitioners confronted with pulmonary diseases." (Experimental and Toxicologic Pathology)
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Extra info for Analytical Lung Pathology
The adjacent lung tissue is unsuspicious. ~ Descriptors: Lung parenchyma with altered structure: • noncaseous epithelioid granulomas • fungus (intragranulomatous, adiaspores) • multinucleated giant cells • palisading histiocytes • focal interstitial fibrosis • Special stains: PAS, Mayer's mucicarmine technique, Gridley, gallocyanin, toluidine blue. Hallmark of diagnosis: Demonstration of adiaconidia embedded in granulomatous collagenous tissue with scattered giant cells. Differential diagnosis: Lentil pneumonia (grain aspiration).
Hyaline membranes and focal necrosis of interalveolar septula may be present. Inclusion bodies can be found in the bronchiolar epithelium and in the cells of the alveolar lining. They occur in two types: one showing a homogeneous, basophilic or amphophilic, Feulgen-positive inclusion located in an enlarged so-called smudge cell. The second, less common type of inclusion is smaller, round, eosinophilic, Feulgen-negative, and surrounded by an often incomplete, clear halo. Chronically damaged lungs may proceed to a destructive stage characterized by bronchiectasis, bronchiolitis obliterans, or fibrotic scarring.
39 Allergic (Extrinsic) Alveolitis Prognosis: Usually good. Radiology: Localized, circumscribed, dense infiltrates depending upon the degree of infection. Pathology: Gross: Circumscribed, yellowish-white nodules. Histology: Mixed cellular infiltrates with central necrosis and granulomatous organization including multinucleated giant cells similar to rheumatoid nodules. The organism can be recognized by the yeastlike colonies which consist of endosporulating sporangia. The oval cells contain vacuolated cytoplasm and small, dark nuclei.